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Three more (D3, D4, D5) have now been identifiedand cloned. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B (1992) Ampli?cation of a geneencoding a p53-associated protein in human sarcomas. The terminol-ogy of specific behaviours still raises questions about what constitutes ‘maladaptive’. It is these properties that make it useful as a firstresponder of the adaptive immune system in eliminatingblood-borne pathogens

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